ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3

Article, Other literature type English OPEN
Horiuchi, J; Silverman, N; Piña, B; Marcus, G A; Guarente, L;
  • Publisher: American Society for Microbiology
  • Identifiers: handle: 10261/31237, pmc: PMC232175
  • Subject: Research Article
    mesheuropmc: enzymes and coenzymes (carbohydrates) | immune system diseases | hemic and immune systems | nutritional and metabolic diseases

The ADA genes encode factors which are proposed to function as transcriptional coactivators. Here we describe the cloning, sequencing, and initial characterization of a novel ADA gene, ADA1. Similar to the previously isolated ada mutants, ada1 mutants display decreases ... View more
Share - Bookmark