Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiae.

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Kambris, Zakaria; Blagborough, Andrew M.; Pinto, Sofia B.; Blagrove, Marcus S.C.; Godfray, H. Charles J.; Sinden, Robert E.; Sinkins, Steven P.;
(2010)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS Pathogens,volume 6,issue 10,pagee1001143 (issn: 1553-7366, eissn: 1553-7374)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC2951381, doi: 10.1371/journal.ppat.1001143
  • Subject: Insect Proteins | INFECTION | RC581-607 | Research Article | Wolbachia | VIRULENT WOLBACHIA | Malaria | Immunologic diseases. Allergy | Genetics and Genomics/Genetics of the Immune System | MOSQUITO AEDES-AEGYPTI | TRANSMISSION | Animals | Female | CYTOPLASMIC INCOMPATIBILITY | Immunology | Antibiosis | Genetics and Genomics/Disease Models | Animals, Genetically Modified | Life Sciences & Biomedicine | Communicable Disease Control | Plasmodium | Microbiology | QH301-705.5 | Gene Expression Regulation | Up-Regulation | STRAIN WMELPOP | Medical Microbiology | LIFE-SHORTENING WOLBACHIA | Gene Knockdown Techniques | Science & Technology | DROSOPHILA | Virology | Immunity, Innate | Anopheles gambiae | PATHOGEN | Host-Parasite Interactions | MALARIA PARASITES | Biology (General) | PARASITOLOGY
    mesheuropmc: parasitic diseases

The over-replicating wMelPop strain of the endosymbiont Wolbachia pipientis has recently been shown to be capable of inducing immune upregulation and inhibition of pathogen transmission in Aedes aegypti mosquitoes. In order to examine whether comparable effects would be... View more
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