Low-Level Detection of Poly(amidoamine) PAMAM Dendrimers Using Immunoimaging Scanning Probe Microscopy

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Cason, Chevelle A.; Fabré, Thomas A.; Buhrlage, Andrew; Haik, Kristi L.; Bullen, Heather A.;
  • Publisher: Hindawi Publishing Corporation
  • Journal: International Journal of Analytical Chemistry,volume 2,012 (issn: 1687-8760, eissn: 1687-8779)
  • Related identifiers: pmc: PMC3296299, doi: 10.1155/2012/341260
  • Subject: Research Article | QD71-142 | Analytical chemistry | Article Subject

Immunoimaging scanning probe microscopy was utilized for the low-level detection and quantification of biotinylated G4 poly(amidoamine) PAMAM dendrimers. Results were compared to those of high-performance liquid chromatography (HPLC) and found to provide a vastly improv... View more
  • References (44)
    44 references, page 1 of 5

    Dykes, G. M.. Dendrimers: a review of their appeal and applications. Journal of Chemical Technology and Biotechnology. 2001; 76 (9): 903-918

    Tomalia, D. A.. Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry. Progress in Polymer Science. 2005; 30 (3-4): 294-324

    Tomalia, D. A., Mark, J. E.. The emergence of a new macromolecular architecture: the dendritic state. Physical Properties of Polymers Handbook. 2007: 671-692

    Tomalia, D. A., Henderson, S. A., Diallo, M. S., Goddard, W. A. I., Brenner, D. W., Lyshevski, S. E., Irafrate, G. J.. Dendrimers—an enabling synthetic science to controlled organic nanostructures. Handbook of Nanoscience, Engineering and Technology. 2007: 24.1-24.47

    Astruc, D., Boisselier, E., Ornelas, C.. Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics, and nanomedicine. Chemical Reviews. 2010; 110 (4): 1857-1959

    Gajbhiye, V., Palanirajan, V. K., Tekade, R. K., Jain, N. K.. Dendrimers as therapeutic agents: a systematic review. Journal of Pharmacy and Pharmacology. 2009; 61 (8): 989-1003

    Wijagkanalan, W., Kawakami, S., Hashida, M.. Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Pharmaceutical Research. 2011; 28 (7): 1500-1519

    Petkar, K. C., Chavhan, S. S., Agatonovik-Kustrin, S., Sawant, K. K.. Nanostructured materials in drug and gene delivery: a review of the state of the art. Critical Reviews in Therapeutic Drug Carrier Systems. 2011; 28 (2): 101-164

    Mintzer, M. A., Grinstaff, M. W.. Biomedical applications of dendrimers: a tutorial. Chemical Society Reviews. 2011; 40 (1): 173-190

    Cheng, Y., Zhao, L., Li, Y., Xu, T.. Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives. Chemical Society Reviews. 2011; 40 (5): 2673-2703

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