Ciproxifan, a Histamine H 3 -Receptor Antagonist/Inverse Agonist, Potentiates Neurochemical and Behavioral Effects of Haloperidol in the Rat

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Pillot , Catherine; Ortiz , Jordi; Héron , Anne; Ridray , Sophie; Schwartz , Jean-Charles; Arrang , Jean-Michel;
(2002)
  • Publisher: Society for Neuroscience
  • Subject: H 3 receptor | neurotensin | histamine | ciproxifan | [ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] | Dopamine D2 receptors | [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] | c-fos | D 2 receptor | [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology | [ SDV.NEU.NB ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology | catalepsy | haloperidol | enkephalin | antagonist/ inverse agonist | [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology | [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology | Histamine H3 receptor | locomotor activity | [ SDV.SP.PHARMA ] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology | [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology | in situ hybridization
    mesheuropmc: nervous system

International audience; By using double in situ hybridization performed with proen-kephalin and H 3-receptor riboprobes on the same sections from rat brain, we show that histamine H 3 receptors are expressed within striatopallidal neurons of the indirect movement pathwa... View more
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