Thymoquinone restores liver fibrosis and improves oxidative stress status in a lipopolysaccharide-induced inflammation model in rats

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Asgharzadeh, Fereshteh ; Bargi, Rahimeh ; Beheshti, Farimah ; Hosseini, Mahmoud ; Farzadnia, Mehdi ; Khazaei, Majid (2017)
  • Publisher: Mashhad University of Medical Sciences
  • Journal: Avicenna Journal of Phytomedicine, volume 7, issue 6, pages 502-510 (issn: 2228-7930, eissn: 2228-7949)
  • Related identifiers: doi: 10.22038/ajp.2017.21744.1815, pmc: PMC5745534
  • Subject: Thymoquinone | Original Article | RM1-950 | Inflammation | Liver | Therapeutics. Pharmacology | Fibrosis

Objective: Liver fibrosis is the primary sign of chronic liver injury induced by various causes. Thymoquinone (TQ) is the major ingredient of Nigella sativa with several beneficial effects on the body. In the present study, we aimed to investigate the effect of TQ on li... View more
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