Combined metagenomic and phenomic approaches identify a novel salt tolerance gene from the human gut microbiome

Article English OPEN
Roy D Sleator ; Eamonn eCulligan ; Colin eHill ; Julian eMarchesi (2014)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Microbiology, volume 5 (issn: 1664-302X, eissn: 1664-302X)
  • Related identifiers: doi: 10.3389/fmicb.2014.00189, doi: 10.3389/fmicb.2014.00189/full, pmc: PMC4010731
  • Subject: microbiota | Q1 | gut microbiome | Metagenomics | transcriptional regulator | functional metagenomics | Microbiology | Original Research Article | salt tolerance | BIOLOG | phenotype microarray | QR1-502

In the current study, a number of salt-tolerant clones previously isolated from a human gut metagenomic library were screened using Phenotype MicroArray (PM) technology to assess their functional capacity. PM's can be used to study gene function, pathogenicity, metaboli... View more
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