A small molecule-based strategy for endothelial differentiation and three-dimensional morphogenesis from human embryonic stem cells

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Geng, Yijie ; Feng, Bradley (2016)
  • Publisher: Elsevier
  • Journal: Heliyon, volume 2, issue 7 (issn: 2405-8440, eissn: 2405-8440)
  • Related identifiers: doi: 10.1016/j.heliyon.2016.e00133, pmc: PMC4971129
  • Subject: Cell biology | Social sciences (General) | H1-99 | Science (General) | Developmental biology | Q1-390 | Article

The emerging models of human embryonic stem cell (hESC) self-organizing organoids provide a valuable in vitro platform for studying self-organizing processes that presumably mimic in vivo human developmental events. Here we report that through a chemical screen, we iden... View more
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