Processing of continuously provided punishment and reward in children with ADHD and the modulating effects of stimulant medication: an ERP study.

Article English OPEN
Yvonne Groen ; Oliver Tucha ; Albertus A Wijers ; Monika Althaus
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 8, issue 3 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3605450, doi: 10.1371/journal.pone.0059240
  • Subject: Clinical Psychology | Social and Behavioral Sciences | Attention (Behavior) | Research Article | Biology | Cognitive Psychology | Neuroscience | Mental Health | Motivation | Neuropsychology | Medicine | Experimental Psychology | Q | R | Psychology | Developmental Psychology | Science | Behavior
    mesheuropmc: psychological phenomena and processes | mental disorders | behavioral disciplines and activities

OBJECTIVES: Current models of ADHD suggest abnormal reward and punishment sensitivity, but the exact mechanisms are unclear. This study aims to investigate effects of continuous reward and punishment on the processing of performance feedback in children with ADHD and the modulating effects of stimulant medication. METHODS: 15 Methylphenidate (Mph)-treated and 15 Mph-free children of the ADHD-combined type and 17 control children performed a selective attention task with three feedback conditions: no-feedback, gain and loss. Event Related Potentials (ERPs) time-locked to feedback and errors were computed. RESULTS: All groups performed more accurately with gain and loss than without feedback. Feedback-related ERPs demonstrated no group differences in the feedback P2, but an enhanced late positive potential (LPP) to feedback stimuli (both gains and losses) for Mph-free children with ADHD compared to controls. Feedback-related ERPs in Mph-treated children with ADHD were similar to controls. Correlational analyses in the ADHD groups revealed that the severity of inattention problems correlated negatively with the feedback P2 amplitude and positively with the LPP to losses and omitted gains. CONCLUSIONS: The early selective attention for rewarding and punishing feedback was relatively intact in children with ADHD, but the late feedback processing was deviant (increased feedback LPP). This may explain the often observed positive effects of continuous reinforcement on performance and behaviour in children with ADHD. However, these group findings cannot be generalised to all individuals with the ADHD, because the feedback-related ERPs were associated with the severity of the inattention problems. Children with ADHD-combined type with more inattention problems showed both deviant early attentional selection of feedback stimuli, and deviant late processing of non-reward and punishment.
Share - Bookmark