Effects of o-vanillin on K+ transport of red blood cells from patients with sickle cell disease

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Hannemann, A.; Cytlak, U.M.C.; Gbotosho, O.T.; Rees, D.C.; Tewari, S.; Gibson, J.S.;
(2014)

Aromatic aldehydes like o-vanillin were designed to reduce the complications of sickle cell disease (SCD) by interaction with HbS, to reduce polymerisation and RBC sickling. Present results show that o-vanillin also directly affects RBC membrane permeability. Both the K... View more
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