Effectiveness and cost-effectiveness of daily all-over-body application of emollient during the first year of life for preventing atopic eczema in high-risk children (The BEEP trial): protocol for a randomised controlled trial.

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Chalmers, J.R.; Haines, R.H.; Mitchell, E.J.; Thomas, K.S.; Brown, S.J.; Ridd, M.; Lawton, S.; Simpson, E.L.; Cork, M.J.; Sach, T.H.; Bradshaw, L.E.; Montgomery, A.A.; Boyle, R.J.; Williams, H.C.;
(2017)
  • Publisher: BioMed Central
  • Journal: Trials,volume 18 (issn: 1745-6215, eissn: 1745-6215)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1186/s13063-017-2031-3, pmc: PMC5521124
  • Subject: /dk/atira/pure/researchoutput/pubmedpublicationtype/D016449 | /dk/atira/pure/researchoutput/pubmedpublicationtype/D016448 | /dk/atira/pure/researchoutput/pubmedpublicationtype/D065007 | /dk/atira/pure/researchoutput/pubmedpublicationtype/D016428 | /dk/atira/pure/researchoutput/pubmedpublicationtype/D013485 | Core outcomes | R5-920 | Protocol, randomised controlled trial, eczema, atopic dermatitis, prevention, emollient, barrier enhancement, filaggrin, core outcomes | Randomised controlled trial | Atopic dermatitis | Emollient | Barrier enhancement | Research Support, Non-U.S. Gov't | Pragmatic Clinical Trial | Randomized Controlled Trial | Protocol | Medicine (General) | Eczema | Study Protocol | Journal Article | Multicenter Study | Filaggrin | Prevention

Background Atopic eczema (AE) is a common skin problem that impairs quality of life and is associated with the development of other atopic diseases including asthma, food allergy and allergic rhinitis. AE treatment is a significant cost burden for health care providers.... View more
  • References (44)
    44 references, page 1 of 5

    1. Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, et al. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol. 2004;113(5):832-6.

    2. Malik G, Tagiyeva N, Aucott L, McNeill G, Turner SW. Changing trends in asthma in 9-12 year olds between 1964 and 2009. Arch Dis Child. 2011;96(3):227-31.

    3. Odhiambo JA, Williams HC, Clayton TO, Robertson CF, Asher MI. Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three. J Allergy Clin Immunol. 2009;124(6):1251-8. e23.

    4. Williams HC, Wüthrich B. Atopic dermatitis; The epidemiology, causes and prevention of atopic eczema. Cambridge University Press; 2000

    5. Kemp AS. Cost of illness of atopic dermatitis in children: a societal perspective. Pharmacoeconomics. 2003;21(2):105-13.

    6. Martin PE, Eckert JK, Koplin JJ, Lowe AJ, Gurrin LC, Dharmage SC, et al. Which infants with eczema are at risk of food allergy? Results from a population-based cohort. Clin Exp Allergy. 2015;45(1):255-64.

    7. van der Hulst AE, Klip H, Brand PL. Risk of developing asthma in young children with atopic eczema: a systematic review. J Allergy Clin Immunol. 2007;120(3):565-9.

    8. von Kobyletzki LB, Bornehag CG, Hasselgren M, Larsson M, Lindstrom CB, Svensson A. Eczema in early childhood is strongly associated with the development of asthma and rhinitis in a prospective cohort. BMC Dermatol. 2012;12:11.

    9. Punekar YS, Sheikh A. Establishing the sequential progression of multiple allergic diagnoses in a UK birth cohort using the General Practice Research Database. Clin Exp Allergy. 2009;39(12):1889-95.

    10. Zheng T, Yu J, Oh MH, Zhu Z. The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma. Allergy, Asthma Immunol Res. 2011;3(2):67-73.

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