publication . Other literature type . Article . 1996

Apoptosis and T-cell depletion during feline infectious peritonitis.

Horzinek, M.C.; Haagmans, B.L.; Egberink, H.F.;
Open Access English
  • Published: 01 Dec 1996
Abstract
Cats that have succumbed to feline infectious peritonitis, an immune- mediated disease caused by variants of feline coronaviruses, show apoptosis and T-cell depletion in their lymphoid organs. The ascitic fluid that develops in the course of the condition causes apoptosis in vitro but only in activated T cells. Since feline infectious peritonitis virus does not infect T cells, and viral proteins did not inhibit T-cell proliferation, we postulate that soluble mediators released during the infection cause apoptosis and T-cell depletion.
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Other literature type . 1996
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publication . Other literature type . Article . 1996

Apoptosis and T-cell depletion during feline infectious peritonitis.

Horzinek, M.C.; Haagmans, B.L.; Egberink, H.F.;