Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster.

Article English OPEN
Haag-Liautard, C.; Coffey, N.; Houle, D.; Lynch, M.; Charlesworth, B.; Keightley, P. D.;
(2008)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS Biology (issn: 1544-9173, eissn: 1545-7885)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pbio.0060204
  • Subject: /dk/atira/pure/subjectarea/asjc/1100 | Agricultural and Biological Sciences(all) | Neuroscience(all) | Biochemistry, Genetics and Molecular Biology(all) | Immunology and Microbiology(all) | performance liquid-chromatography; caenorhabditis-elegans; comparative genomics; selection; transmission; divergence; nucleotide; evolution; simulans; disease | /dk/atira/pure/subjectarea/asjc/1300 | /dk/atira/pure/subjectarea/asjc/2400 | /dk/atira/pure/subjectarea/asjc/2800 | Biology (General) | QH301-705.5

Mitochondrial DNA (mtDNA) variants are widely used in evolutionary genetics as markers for population history and to estimate divergence times among taxa. Inferences of species history are generally based on phylogenetic comparisons, which assume that molecular evolutio... View more
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