Polyelectrolyte Complex Nanoparticles of Poly(ethyleneimine) and Poly(acrylic acid): Preparation and Applications

Article, Other literature type English OPEN
Martin Müller; Bernd Keßler; Sebastian Poeschla; Bernhard Torger; Johanna Fröhlich;
  • Publisher: Molecular Diversity Preservation International
  • Journal: Polymers (issn: 2073-4360)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.3390/polym3020762
  • Subject: polymer nanoparticles | colloid coagulation | cellulose modification | Organic chemistry | QD241-441 | poly(acrylic acid) | poly(ethyleneimine) | polyelectrolyte complex | drug delivery

In this contribution we outline polyelectrolyte (PEL) complex (PEC) nanoparticles, prepared by mixing solutions of the low cost PEL components poly(ethyleneimine) (PEI) and poly(acrylic acid) (PAC). It was found, that the size and internal structure of PEI/PAC particles... View more
  • References (36)
    36 references, page 1 of 4

    1. Lasic, D.D. Sterically stabilized vesicles. Angew. Chem. Int. Ed. 1994, 33, 1685-1698.

    2. Antonietti, M; Förster, S. Vesicles and liposomes: A self-assembly principle beyond lipids. Adv. Mater. 2003, 15, 1323-1333.

    3. Donath, E.; Sukhorukov, G.B.; Caruso, F.; Davis, S.; Möhwald, H. Novel hollow polymer shells by colloid-templated assembly of polyelectrolytes. Angew. Chem. Int. Ed. 1998, 37, 2202-2205.

    4. Sukhorukov, G.B.; Rogach, A.L.; Zebli, B.; Liedl, T.; Skirtach, A.G.; Köhler, K.;Antipov, A.A.; Gaponik, N.; Susha, A.S.; Winterhalter, M.; Parak, W.J. Nanoengineered polymer capsules: Tools for detection, controlled delivery, and site-specific manipulation. Small 2005, 182, 194-200.

    5. Michaels, A.S. Polyelectrolyte complexes. Ind. Eng. Chem. 1965, 57, 32.

    6. Kabanov, V.A.; Zezin, A.B. Soluble interpolymeric complexes as a new class of synthetic polyelectrolytes. Pure Appl. Chem. 1984, 56, 343.

    7. Philipp, B.; Dautzenberg, H.; Linow, K.J.; Kötz, J.; Dawydoff, W. Polyelectrolyte complexesRecent developments and open problems. Progr. Polym. Sci. 1989, 14, 91.

    8. Dubin, P.; Bock, J.; Davies, R.M.; Schulz, D.N.; Thies, C. Macromolecular Complexes in Chemistry and Biology; Springer-Verlag: Berlin, Germany, 1994.

    9. Harada, A.; Kataoka, K. Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely charged block-copolymers with poly(ethylene glycol) segments. Macromolecules 1995, 28, 5294-5299.

    10. Harada-Shiba, M.; Yamauchi, K.; Harada A.; Takamisawa I.; Shimokado, K.; Kataoka, K. Polyion complex micelles as vectors in gene therapy-pharmacokinetics and in vivo gene transfer. Gene Therapy 2002, 9, 407-414.

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