HIF-1-dependent regulation of lifespan in Caenorhabditis elegans by the acyl-CoA-binding protein MAA-1

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Shamalnasab, Mehrnaz; Dhaoui, Manel; Thondamal, Manjunatha; Harvald, Eva Bang; Færgeman, Nils J; Aguilaniu, Hugo; Fabrizio, Paola;
  • Publisher: Impact Journals LLC
  • Journal: volume 9,issue 7,pages1,745-1,769issn: 1945-4589, eissn: 1945-4589
  • Related identifiers: doi: 10.18632/aging.101267, pmc: PMC5559173
  • Subject: C. elegans | HIF-1 | Journal Article | aging | proteostasis | Research Paper | ACBP

<p>In yeast, the broadly conserved acyl-CoA-binding protein (ACBP) is a negative regulator of stress resistance and longevity. Here, we have turned to the nematode C. elegans as a model organism in which to determine whether ACBPs play similar roles in multicellular org... View more
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