CETP Expression Protects Female Mice from Obesity-Induced Decline in Exercise Capacity.

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David A Cappel ; Louise Lantier ; Brian T Palmisano ; David H Wasserman ; John M Stafford
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 10, issue 8 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0136915, pmc: PMC4551677
  • Subject: Q | R | Research Article | Science | Medicine
    mesheuropmc: carbohydrates (lipids) | lipids (amino acids, peptides, and proteins)

Pharmacological approaches to reduce obesity have not resulted in dramatic reductions in the risk of coronary heart disease (CHD). Exercise, in contrast, reduces CHD risk even in the setting of obesity. Cholesteryl Ester Transfer Protein (CETP) is a lipid transfer prote... View more
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