High Salt Intake Increases Blood Pressure via BDNF-Mediated Downregulation of KCC2 and Impaired Baroreflex Inhibition of Vasopressin Neurons

Article, Other literature type English OPEN
Choe, Katrina Y.; Han, Su Y.; Gaub, Perrine; Shell, Brent; Voisin, Daniel L.; Knapp, Blayne A.; Barker, Philip A.; Brown, Colin H.; Cunningham, J. Thomas; Bourque, Charles W.;
(2015)

The mechanisms by which dietary salt promotes hypertension are unknown. Previous work established that plasma [Na+] and osmolality rise in proportion with salt intake and thus promote release of vasopressin (VP) from the neurohypophysis. Although high levels of circulat... View more
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