High Salt Intake Increases Blood Pressure via BDNF-Mediated Downregulation of KCC2 and Impaired Baroreflex Inhibition of Vasopressin Neurons

Article, Other literature type English OPEN
Choe, Katrina Y. ; Han, Su Y. ; Gaub, Perrine ; Shell, Brent ; Voisin, Daniel L. ; Knapp, Blayne A. ; Barker, Philip A. ; Brown, Colin H. ; Cunningham, J. Thomas ; Bourque, Charles W. (2015)

The mechanisms by which dietary salt promotes hypertension are unknown. Previous work established that plasma [Na+] and osmolality rise in proportion with salt intake and thus promote release of vasopressin (VP) from the neurohypophysis. Although high levels of circulat... View more
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