Dialogue inter-règne entre Pseudomonas aeruginosa et les cellules de l'immunité innée. Rôle de la production de L-kynurénine par les bactéries

Doctoral thesis French OPEN
Genestet, Charlotte;
(2014)
  • Publisher: HAL CCSD
  • Subject: Interkingdom dialogue | [ SDV.IB ] Life Sciences [q-bio]/Bioengineering | Innate immunity | Immunité innée | Dialogue inter-règne | Psedomonas aeruginosa | Kynurénine | [SDV.IB]Life Sciences [q-bio]/Bioengineering

Pseudomonas aeruginosa is responsible for persistent infections in cystic fibrosis patients, suggesting an ability to circumvent innate immune defenses. Many host cells produce kynurenine, which is known to control immune system homeostasis. Interestingly this bacterium... View more
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