Peroxisomes in brain development and function

Article English OPEN
Berger, Johannes; Dorninger, Fabian; Forss-Petter, Sonja; Kunze, Markus;
(2016)
  • Publisher: Elsevier BV
  • Journal: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, volume 1,863, issue 5, pages 934-955 (issn: 0167-4889)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1016/j.bbamcr.2015.12.005, pmc: PMC4880039
  • Subject: Molecular Biology | Cell Biology | Lipid metabolism | Rhizomelic chondrodysplasia punctata | Plasmalogen | X-linked adrenoleukodystrophy | Article | D-bifunctional protein deficiency | Zellweger spectrum disorder

Peroxisomes contain numerous enzymatic activities that are important for mammalian physiology. Patients lacking either all peroxisomal functions or a single enzyme or transporter function typically develop severe neurological deficits, which originate from aberrant deve... View more