Immunological Dysregulation in Multiple Myeloma Microenvironment

Article, Review English OPEN
Romano, Alessandra; Conticello, Concetta; Cavalli, Maide; Vetro, Calogero; La Fauci, Alessia; Parrinello, Nunziatina Laura; Di Raimondo, Francesco;
  • Publisher: Hindawi Publishing Corporation
  • Journal: BioMed Research International,volume 2,014 (issn: 2314-6133, eissn: 2314-6141)
  • Related identifiers: pmc: PMC4071780, doi: 10.1155/2014/198539
  • Subject: Review Article | R | Medicine | Article Subject

Multiple Myeloma (MM) is a systemic hematologic disease due to uncontrolled proliferation of monoclonal plasma cells (PC) in bone marrow (BM). Emerging in other solid and liquid cancers, the host immune system and the microenvironment have a pivotal role for PC growth, ... View more
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