publication . Other literature type . Article . 2014

Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry Measurement of Caffeine in Caffeine-Laced Pants and in Urine and Skin of a Pants User

Manuela Pellegrini; Daniela De Orsi; Carmine Guarino; Maria Concetta Rotolo; Rita di Giovannandrea; Roberta Pacifici; Simona Pichini;
Open Access English
  • Published: 15 Apr 2014 Journal: Cosmetics (issn: 2079-9284, Copyright policy)
  • Publisher: Multidisciplinary Digital Publishing Institute
Abstract
A fast and sensitive ultra-performance liquid chromatography tandem mass spectrometry method was developed for the measurement of caffeine in caffeine-laced pants and in urine and skin of a pants user. The substance and its internal standard (N-ethylnorcotinine) were separated by reversed phase chromatography with 5 mM ammonium formate pH 3.0 and 0.3% formic acid in acetonitrile mobile phase (83:17 v/v) by isocratic elution and detected by tandem mass spectrometry operated in multiple reaction monitoring mode via positive electrospray ionization. Linearity was studied from 1.4 to100 ng/mL range for urine, from 5 to 100 ng/cotton swab for skin caffeine and from...
Subjects
free text keywords: Chemistry, caffeine laced pants, tandem mass spectrometry, cosmetotextile, QD1-999, ultra-performance liquid chromatography
19 references, page 1 of 2

1. Al-Bader, T.; Byrne, A.; Gillbro, J.; Mitarotonda, A.; Metois, A.; Vial, F.; Rawlings, A.V.; Laloeuf, A. Effect of cosmetic ingredients as anticellulite agents: Synergistic action of actives with in vitro and in vivo efficacy. J. Cosmet. Dermatol. 2012, 11, 17-26.

2. Khan, M.H.; Victor, F.; Rao, B.; Sadick, N.S. Treatment of cellulite: Part I. Pathophysiology. J. Am. Acad. Dermatol. 2010, 62, 361-370.

3. Hexsel, D.; Orlandi, C.; Zechmeister do Prado, D. Botanical extracts used in the treatment of cellulite. Dermatol. Surg. 2005, 31, 866-872.

4. Rawlings, A.V. Cellulite and its treatment. Int. J. Cosmet. Sci. 2006, 28, 175-190.

5. Roure, R.; Oddos, T.; Rossi, A.; Vial, F.; Bertin, C. Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, in vitro, ex vivo and in vivo studies. Int. J. Cosmet. Sci. 2011, 33, 519-526.

6. Barel, A.O.; Paye, M.; Maibach, H.I. Handbook of Cosmetic Science and Technology; CRC Press: New York, NY, USA, 2001.

7. Lupi, O.; Semenovitch, I.J.; Treu, C.; Bottino, D.; Bouskela, E. Evaluation of the effects of caffeine in the microcirculation and edema on thighs and buttocks using the orthogonal polarization spectral imaging and clinical parameters. J. Cosmet. Dermatol. 2007, 6, 102-107.

8. Velasco, M.V.; Tano, C.T.; Machado-Santelli, G.M.; Consiglieri, V.O.; Kaneko, T.M.; Baby, A.R. Effects of caffeine and siloxanetriol alginate caffeine, as anticellulite agents, on fatty tissue: Histological evaluation. J. Cosmet. Dermatol. 2008, 7, 23-29.

9. Pires-de-Campos, M.S.; Leonardi, G.R.; Chorilli, M.; Spadari-Bratfisch, R.C.; Polacow, M.L.; Grassi-Kassisse, D.M. The effect of topical caffeine on the morphology of swine hypodermis as measured by ultrasound. J. Cosmet. Dermatol. 2008, 7, 232-237.

10. Buschmann, H.J.; Schollmeyer, E. Applications of cyclodextrins in cosmetic products: A review. J. Cosmet. Sci. 2002, 53, 185-191.

11. Bhaskara-Amrit, U.R.; Agrawal, P.B.; Warmoeskerken, M.M.C.G. Applications of β-cyclodextrins in textiles. AUTEX Res. J. 2011, 11, 94-101. [OpenAIRE]

12. European Committee for Standardization. Available online: http://www.cen.eu/CEN/Sectors/ TechnicalCommitteesWorkshops/CENTechnicalCommittees/Pages/Standards.aspx?param=6229 &title=CEN%2FTC+248 (accessed on 10 April 2014).

13. Regulation n. (CE) 1223/2009 of the European Parliament. Available online: http://eur-lex.europa.eu/ LexUriServ/LexUriServ.do?uri=CELEX:32009R1223:it:NOT (accessed on 30 November 2009).

14. Regulation n. (CE) 1007/2011 of the European Parliament. Available online: http://eur-lex.europa.eu/ LexUriServ/LexUriServ.do?uri=CELEX:32011R1007:IT:NOT (accessed on 27 September 2011).

15. ICH Topic Q 2 (R1) Validation of Analytical Procedures: Text and Methodology. Available online: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/ WC500002662.pdf (accessed on 10 April 2014).

19 references, page 1 of 2
Similar Outcomes
Abstract
A fast and sensitive ultra-performance liquid chromatography tandem mass spectrometry method was developed for the measurement of caffeine in caffeine-laced pants and in urine and skin of a pants user. The substance and its internal standard (N-ethylnorcotinine) were separated by reversed phase chromatography with 5 mM ammonium formate pH 3.0 and 0.3% formic acid in acetonitrile mobile phase (83:17 v/v) by isocratic elution and detected by tandem mass spectrometry operated in multiple reaction monitoring mode via positive electrospray ionization. Linearity was studied from 1.4 to100 ng/mL range for urine, from 5 to 100 ng/cotton swab for skin caffeine and from...
Subjects
free text keywords: Chemistry, caffeine laced pants, tandem mass spectrometry, cosmetotextile, QD1-999, ultra-performance liquid chromatography
19 references, page 1 of 2

1. Al-Bader, T.; Byrne, A.; Gillbro, J.; Mitarotonda, A.; Metois, A.; Vial, F.; Rawlings, A.V.; Laloeuf, A. Effect of cosmetic ingredients as anticellulite agents: Synergistic action of actives with in vitro and in vivo efficacy. J. Cosmet. Dermatol. 2012, 11, 17-26.

2. Khan, M.H.; Victor, F.; Rao, B.; Sadick, N.S. Treatment of cellulite: Part I. Pathophysiology. J. Am. Acad. Dermatol. 2010, 62, 361-370.

3. Hexsel, D.; Orlandi, C.; Zechmeister do Prado, D. Botanical extracts used in the treatment of cellulite. Dermatol. Surg. 2005, 31, 866-872.

4. Rawlings, A.V. Cellulite and its treatment. Int. J. Cosmet. Sci. 2006, 28, 175-190.

5. Roure, R.; Oddos, T.; Rossi, A.; Vial, F.; Bertin, C. Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, in vitro, ex vivo and in vivo studies. Int. J. Cosmet. Sci. 2011, 33, 519-526.

6. Barel, A.O.; Paye, M.; Maibach, H.I. Handbook of Cosmetic Science and Technology; CRC Press: New York, NY, USA, 2001.

7. Lupi, O.; Semenovitch, I.J.; Treu, C.; Bottino, D.; Bouskela, E. Evaluation of the effects of caffeine in the microcirculation and edema on thighs and buttocks using the orthogonal polarization spectral imaging and clinical parameters. J. Cosmet. Dermatol. 2007, 6, 102-107.

8. Velasco, M.V.; Tano, C.T.; Machado-Santelli, G.M.; Consiglieri, V.O.; Kaneko, T.M.; Baby, A.R. Effects of caffeine and siloxanetriol alginate caffeine, as anticellulite agents, on fatty tissue: Histological evaluation. J. Cosmet. Dermatol. 2008, 7, 23-29.

9. Pires-de-Campos, M.S.; Leonardi, G.R.; Chorilli, M.; Spadari-Bratfisch, R.C.; Polacow, M.L.; Grassi-Kassisse, D.M. The effect of topical caffeine on the morphology of swine hypodermis as measured by ultrasound. J. Cosmet. Dermatol. 2008, 7, 232-237.

10. Buschmann, H.J.; Schollmeyer, E. Applications of cyclodextrins in cosmetic products: A review. J. Cosmet. Sci. 2002, 53, 185-191.

11. Bhaskara-Amrit, U.R.; Agrawal, P.B.; Warmoeskerken, M.M.C.G. Applications of β-cyclodextrins in textiles. AUTEX Res. J. 2011, 11, 94-101. [OpenAIRE]

12. European Committee for Standardization. Available online: http://www.cen.eu/CEN/Sectors/ TechnicalCommitteesWorkshops/CENTechnicalCommittees/Pages/Standards.aspx?param=6229 &title=CEN%2FTC+248 (accessed on 10 April 2014).

13. Regulation n. (CE) 1223/2009 of the European Parliament. Available online: http://eur-lex.europa.eu/ LexUriServ/LexUriServ.do?uri=CELEX:32009R1223:it:NOT (accessed on 30 November 2009).

14. Regulation n. (CE) 1007/2011 of the European Parliament. Available online: http://eur-lex.europa.eu/ LexUriServ/LexUriServ.do?uri=CELEX:32011R1007:IT:NOT (accessed on 27 September 2011).

15. ICH Topic Q 2 (R1) Validation of Analytical Procedures: Text and Methodology. Available online: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/ WC500002662.pdf (accessed on 10 April 2014).

19 references, page 1 of 2
Similar Outcomes
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publication . Other literature type . Article . 2014

Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry Measurement of Caffeine in Caffeine-Laced Pants and in Urine and Skin of a Pants User

Manuela Pellegrini; Daniela De Orsi; Carmine Guarino; Maria Concetta Rotolo; Rita di Giovannandrea; Roberta Pacifici; Simona Pichini;