Association between cytochrome CYP17A1, CYP3A4, and CYP3A43 polymorphisms and prostate cancer risk and aggressiveness in a Korean study population

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Han, Jun Hyun; Lee, Yong Seong; Kim, Hae Jong; Lee, Shin Young; Myung, Soon Chul;
  • Publisher: Wolters Kluwer Medknow Publications
  • Journal: Asian Journal of Andrology, volume 17, issue 2, pages 285-291 (issn: 1008-682X, eissn: 1745-7262)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.4103/1008-682X.133320, pmc: PMC4650481
  • Subject: CYP3A4 | androgens; CYP17A1; CYP3A4; CYP3A43; genetics; prostatic neoplasms | Original Article | CYP3A43 | Diseases of the genitourinary system. Urology | RC870-923 | genetics | androgens | CYP17A1 | prostatic neoplasms

In this study, we evaluated genetic variants of the androgen metabolism genes CYP17A1, CYP3A4, and CYP3A43 to determine whether they play a role in the development of prostate cancer (PCa) in Korean men. The study population included 240 pathologically diagnosed cases o... View more
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