miREM: an expectation-maximization approach for prioritizing miRNAs associated with gene-set

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Abdul Hadi, Luqman Hakim; Xuan Lin, Quy Xiao; Minh, Tri Tran; Loh, Marie; Ng, Hong Kiat; Salim, Agus; Soong, Richie; Benoukraf, Touati;

Background The knowledge of miRNAs regulating the expression of sets of mRNAs has led to novel insights into numerous and diverse cellular mechanisms. While a single miRNA may regulate many genes, one gene can be regulated by multiple miRNAs, presenting a complex relati... View more
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