Preclinical Assessment of Viral Vectored and Protein Vaccines Targeting the Duffy-Binding Protein Region II of Plasmodium Vivax

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de Cassan, Simone C. ; Shakri, A. Rushdi ; Llewellyn, David ; Elias, Sean C. ; Cho, Jee Sun ; Goodman, Anna L. ; Jin, Jing ; Douglas, Alexander D. ; Suwanarusk, Rossarin ; Nosten, François H. ; Rénia, Laurent ; Russell, Bruce ; Chitnis, Chetan E. ; Draper, Simon J. (2015)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Immunology, volume 6 (issn: 1664-3224, eissn: 1664-3224)
  • Related identifiers: pmc: PMC4495344, doi: 10.3389/fimmu.2015.00348
  • Subject: blood-stage | vaccine | Plasmodium vivax | adenovirus | poxvirus | MVA | Original Research | malaria | Immunology | Duffy-binding protein
    mesheuropmc: parasitic diseases

Malaria vaccine development has largely focused on Plasmodium falciparum; however, a reawakening to the importance of Plasmodium vivax has spurred efforts to develop vaccines against this difficult to treat and at times severe form of relapsing malaria, which constitute... View more