Duchenne muscular dystrophy models show their age

Article, Other literature type English OPEN
Chamberlain, Jeffrey S.;
(2010)
  • Publisher: Elsevier BV
  • Journal: Cell,volume 143,issue 7,pages1,040-1,042 (issn: 0092-8674)
  • Related identifiers: pmc: PMC3038548, doi: 10.1016/j.cell.2010.12.005
  • Subject: Biochemistry, Genetics and Molecular Biology(all) | Article
    mesheuropmc: congenital, hereditary, and neonatal diseases and abnormalities | musculoskeletal diseases

The lack of appropriate animal models has hampered efforts to develop therapies for Duchenne muscular dystrophy (DMD). A new mouse model lacking both dystrophin and telomerase (Sacco et al., 2010) closely mimics the pathological progression of human DMD and shows that m... View more
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