Epididymosomes: transfer of fertility-modulating proteins to the sperm surface

Article English OPEN
Patricia A Martin-DeLeon;
  • Publisher: Medknow Publications & Media Pvt Ltd
  • Journal: Asian Journal of Andrology,volume 17,issue 5,pages720-725 (issn: 1008-682X, eissn: 1745-7262)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.4103/1008-682X.155538, pmc: PMC4577579
  • Subject: transmembrane proteins | Diseases of the genitourinary system. Urology | epididymal maturation; epididymal secretory proteins; GPI-linked proteins; lipid carrier; membrane-associated proteins; PMCA4; transmembrane proteins | PMCA4 | membrane-associated proteins | GPI-linked proteins | epididymal secretory proteins | RC870-923 | Invited Review | lipid carrier | epididymal maturation
    mesheuropmc: endocrine system | reproductive and urinary physiology | urogenital system

A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation. These proteins serve roles in immunoprotection and in key steps of fertilization such as capacitation, acrosomal exo... View more
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