S-Propargyl-cysteine Exerts a Novel Protective Effect on Methionine and Choline Deficient Diet-Induced Fatty Liver via Akt/Nrf2/HO-1 Pathway

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Li, Wenwen; Ma, Fenfen; Zhang, Laiyin; Huang, Yong; Li, Xinghui; Zhang, Aijie; Hou, Cuilan; Zhu, Yichun; Zhu, YiZhun;
  • Publisher: Hindawi Publishing Corporation
  • Journal: Oxidative Medicine and Cellular Longevity,volume 2,016 (issn: 1942-0900, eissn: 1942-0994)
  • Related identifiers: doi: 10.1155/2016/4690857, pmc: PMC4893438
  • Subject: Cytology | Research Article | QH573-671 | Article Subject

This study investigated the antioxidative effect of S-propargyl-cysteine (SPRC) on nonalcoholic fatty liver (NAFLD) by treating mice fed a methionine and choline deficient (MCD) diet with SPRC for four weeks. We found that SPRC significantly reduced hepatic reactive oxy... View more
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