Encephalitis due to antibodies to voltage gated potassium channel (VGKC) with cerebellar involvement in a teenager

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Langille, Megan M. ; Desai, Jay (2015)
  • Publisher: Medknow Publications & Media Pvt Ltd
  • Journal: Annals of Indian Academy of Neurology, volume 18, issue 2, pages 238-239 (issn: 0972-2327, eissn: 1998-3549)
  • Related identifiers: doi: 10.4103/0972-2327.150623, pmc: PMC4445206
  • Subject: Neurology. Diseases of the nervous system | anti-VGKC | encephalitis | RC346-429 | Case Report | voltage gated potassium channel | Antibodies to voltage gated potassium channel | VGKC

Encephalitis due to antibodies to voltage gated potassium channel (VGKC) typically presents with limbic encephalitis and medial temporal lobe involvement on neuroimaging. We describe a case of 13 year girl female with encephalitis due to antibodies to VGKC with signal changes in the cerebellar dentate nuclei bilaterally and clinical features that suggested predominant cerebellar involvement. These have never been reported previously in the literature. Our case expands the phenotypic spectrum of this rare condition.
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