CTCF Mediates the Cell-Type Specific Spatial Organization of the Kcnq5 Locus and the Local Gene Regulation
- Publisher: Public Library of Science
(issn: 1932-6203, eissn: 1932-6203)
Q | R | Research Article | Biology | Genetics | Molecular Cell Biology | Science | Genomics | Medicine
Chromatin loops play important roles in the dynamic spatial organization of genes in the nucleus. Growing evidence has revealed that the multivalent functional zinc finger protein CCCTC-binding factor (CTCF) is a master regulator of genome spatial organization, and medi...