Further investigation of the role of HLA-DPB1 in adult Hodgkin's disease (HD) suggests an influence on susceptibility to different HD subtypes

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Taylor, G M ; Gokhale, D A ; Crowther, D ; Woll, P J ; Harris, M ; Ryder, D ; Ayres, M ; Radford, J A (1999)
  • Publisher: Nature Publishing Group
  • Journal: British Journal of Cancer, volume 80, issue 9, pages 1,405-1,411 (issn: 0007-0920, eissn: 1532-1827)
  • Related identifiers: pmc: PMC2363076, doi: 10.1038/sj.bjc.6690536
  • Subject: HLA-DPB1 | Hodgkin's disease | susceptibility | HVR | Regular Article | polymorphic amino acid | resistance

It has been suggested in a number of studies that susceptibility to adult Hodgkin's disease (HD) is influenced by the HLA class II region, and specifically by alleles at the HLA-DPB1 locus. Since HD is diagnostically complex, it is not clear whether different HLA-DPB1 a... View more
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