Stimulation- and palmitoylation-dependent changes in oligomeric conformation of serotonin 5-HT1A receptorsi

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Kobe, Fritz; Renner, Ute; Woehler, Andrew; Wlodarczyk, Jakub; Papusheva, Ekaterina; Bao, Guobin; Zeug, André; Richter, Diethelm W.; Neher, Erwin; Ponimaskin, Evgeni;
  • Publisher: Elsevier BV
  • Journal: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research,volume 1,783,issue 8,pages1,503-1,516 (issn: 0167-4889)
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  • Related identifiers: doi: 10.1016/j.bbamcr.2008.02.021
  • Subject: Molecular Biology | Cell Biology | Oligomerization; Serotonin; G-protein coupled receptors; Palmitoylation; Foerster resonance energy transfer

In the present study we analyzed the oligomerization state of the serotonin 5-HT1A receptor and studied oligomerization dynamics in living cells. We also investigated the role of receptor palmitoylation in this process. Biochemical analysis performed in neuroblast... View more