A Glycolipid Adjuvant, 7DW8-5, Enhances CD8+ T Cell Responses Induced by an Adenovirus-Vectored Malaria Vaccine in Non-Human Primates

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Neal N Padte; Mar Boente-Carrera; Chasity D Andrews; Jenny McManus; Brooke F Grasperge; Agegnehu Gettie; Jordana G Coelho-dos-Reis; Xiangming Li; Douglass Wu; Joseph T Bruder; Martha Sedegah; Noelle Patterson; Thomas L Richie; Chi-Huey Wong; David D Ho; Sandhya Vasan; Moriya Tsuji;

A key strategy to a successful vaccine against malaria is to identify and develop new adjuvants that can enhance T-cell responses and improve protective immunity. Upon co-administration with a rodent malaria vaccine in mice, 7DW8-5, a recently identified novel analog of... View more
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