Maternal nutrition modifies trophoblast giant cell phenotype and fetal growth in mice

Article English OPEN
Watkins, Adam J.; Lucas, Emma S.; Marfy-Smith, Stephanie; Bates, Nicola; Kimber, Susan J.; Fleming, Tom P.;
  • Publisher: Bioscientifica Ltd
  • Journal: Reproduction (Cambridge, England),volume 149,issue 6,pages563-575 (issn: 1470-1626, eissn: 1741-7899)
  • Related identifiers: pmc: PMC4418750, doi: 10.1530/REP-14-0667
  • Subject: Research
    mesheuropmc: hemic and lymphatic diseases | embryonic structures

Mammalian placentation is dependent upon the action of trophoblast cells at the time of implantation. Appropriate fetal growth, regulated by maternal nutrition and nutrient transport across the placenta, is a critical factor for adult offspring long-term health. We have... View more