Inhibitory Effect of Arctigenin from Fructus Arctii Extract on Melanin Synthesis via Repression of Tyrosinase Expression

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Park, Hwayong ; Song, Kwang Hoon ; Jung, Pil Mun ; Kim, Ji-Eun ; Ro, Hyunju ; Kim, Mi Yoon ; Ma, Jin Yeul (2013)
  • Publisher: Hindawi Publishing Corporation
  • Journal: Evidence-based Complementary and Alternative Medicine : eCAM, volume 2,013 (issn: 1741-427X, eissn: 1741-4288)
  • Related identifiers: pmc: PMC3678497, doi: 10.1155/2013/965312
  • Subject: Other systems of medicine | Research Article | RZ201-999 | Article Subject

To identify the active compound arctigenin in Fructus Arctii (dried seed of medicinal plant Arctium lappa) and to elucidate the inhibitory mechanism in melanogenesis, we analyzed melanin content and tyrosinase activity on B16BL6 murine melanoma and melan-A cell cultures... View more
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