Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1.

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Antje Müller; Jana Winkler; Franziska Fiedler; Tania Sastradihardja; Claudia Binder; Ralf Schnabel; Jana Kungel; Sven Rothemund; Christian Hennig; Torsten Schöneberg; Simone Prömel;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS Genetics,volume 11,issue 10 (issn: 1553-7390, eissn: 1553-7404)
  • Related identifiers: doi: 10.1371/journal.pgen.1005624, pmc: PMC4624771
  • Subject: QH426-470 | Research Article | Genetics

Orientation of spindles and cell division planes during development of many species ensures that correct cell-cell contacts are established, which is vital for proper tissue formation. This is a tightly regulated process involving a complex interplay of various signals.... View more
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