Constitutive expression of cyclooxygenase 2 transgene in hepatocytes protects against liver injury

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Mayoral , Rafael; Mollá , Belen; Flores , Juana Maria; Boscá , Lisardo; Casado , Marta; Martín Sanz , Paloma;

International audience; The effect of COX-2-dependent prostaglandins (PGs) in acute liver injury has been investigated in transgenic mice that express human COX-2 in hepatocytes. We have used three well established models of liver injury: Lipopolysaccharide injury in D-... View more
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