A Novel System for Identification of Inhibitors of Rift Valley Fever Virus Replication
Other literature type, Article
Piper, Mary E.
Gerrard, Sonja R.
- Publisher: Molecular Diversity Preservation International (MDPI)
(issn: 1999-4915, eissn: 1999-4915)
RNA virus | antivirals | minigenome | Rift Valley fever | <em>Bunyaviridae</em> | virus-like particle | Bunyaviridae | Microbiology | Phlebovirus | QR1-502 | Article
Rift Valley fever virus (RVFV) is a human and livestock pathogen endemic to sub-Saharan Africa. We have developed a T7-dependent system for the efficient production of RVFV-like particles (RVF-VLPs) based on the virulent ZH-501 strain of RVFV. The RVF-VLPs are capable o...