A rapid, sensitive and selective pseudoMRM (pMRM)-based method for the determination of solutol HS15 (SHS15) in rat plasma was developed using liquid chromatography/tandem mass spectrometry (LCâMS/MS). The most abundant ions corresponding to SHS15 free polyethyleneglyco... View more
Bittner, B., Mountfield, R.J.. Intravenous administration of poorly soluble new drug entities in early drug discovery: the potential impact of formulation on pharmacokinetic parameters. Curr. Opin. Drug Discov. Dev.. 2002; 5: 59-71
Sherry, K.U., Ranga, V.. Solutol HS15 as a novel excipient. Pharm. Technol.. 2010: 108-110
6 Technical information, Kolliphor HS15, BASF, 2012, pp. 1–8. 〈http://www.pharma-ingredients.basf.com/Solubilizer/Kolliphor_range/kolliphor_HS15.aspx〉.