Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes

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Ruchti, E.; Roach, P.J.; DePaoli-Roach, A.A.; Magistretti, P.J.; Allaman, I.;
(2016)
  • Publisher: Elsevier BV
  • Journal: IBRO Reports,volume 1,pages46-53 (issn: 2451-8301, eissn: 2451-8301)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1016/j.ibror.2016.10.002, pmc: PMC6084890
  • Subject: NA, Noradrenaline | Insulin | Neurosciences. Biological psychiatry. Neuropsychiatry | PTG, Protein targeting to glycogen | GS, Glycogen synthase | GP, Glycogen phosphorylase | RC321-571 | Noradrenaline | Glia | Glucose metabolism | Article | Ins, Insulin

The storage and use of glycogen, the main energy reserve in the brain, is a metabolic feature of astrocytes. Glycogen synthesis is regulated by Protein Targeting to Glycogen (PTG), a member of specific glycogen-binding subunits of protein phosphatase-1 (PPP1). It positi... View more
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