Subject: Cytology | Research Article | QH573-671 | Article Subject
Chronic obstructive pulmonary disease (COPD) is characterized by lung destruction and inflammation. As a major compound of cigarette smoke, acrolein plays a critical role in the induction of respiratory diseases. GADD34 is known as a growth arrest and DNA damage-related... View more
Stedman, R. L.. The chemical composition of tobacco and tobacco smoke.
Chemical Reviews. 1968; 68 (2): 153-207
Aranyi, C., O'Shea, W. J., Graham, J. A., Miller, F. J.. The effects of inhalation of organic chemical air contaminants on murine lung host defenses.
Fundamental and Applied Toxicology. 1986; 6 (4): 713-720
Hogg, J. C.. Chronic obstructive pulmonary disease: an overview of pathology and pathogenesis.
Novartis Foundation Symposium. 2001; 234: 4-19, 26
Saetta, M.. Airway inflammation in chronic obstructive pulmonary disease.
The American Journal of Respiratory and Critical Care Medicine. 1999; 160 (5, part 2): S17-S20
Lacroix, L., Feng, G., Lotan, R.. Identification of genes expressed differentially in an in vitro human lung carcinogenesis model.
Cancer Biology and Therapy. 2006; 5 (6): 665-673
Wang, H. T., Hu, Y., Tong, D., Huang, J., Gu, L., Wu, X. R., Chung, F. L., Li, G.-M., Tang, M.-S.. Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility.
The Journal of Biological Chemistry. 2012; 287 (15): 12379-12386
Hochman, D. J., Collaco, C. R., Brooks, E. G.. Acrolein induction of oxidative stress and degranulation in mast cells.
Environmental Toxicology. 2014; 29 (8): 908-915
Sun, Y., Ito, S., Nishio, N., Tanaka, Y., Chen, N., Isobe, K.. Acrolein induced both pulmonary inflammation and the death of lung epithelial cells.
Toxicology Letters. 2014; 229 (2): 384-392
Walter, P., Ron, D.. The unfolded protein response: from stress pathway to homeostatic regulation.
Science. 2011; 334 (6059): 1081-1086
Wang, S., Kaufman, R. J.. The impact of the unfolded protein response on human disease.
Journal of Cell Biology. 2012; 197 (7): 857-867