Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function

Article, Review English OPEN
Kosan, Christian; Godmann, Maren;
  • Publisher: Hindawi Publishing Corporation
  • Journal: Stem Cells International,volume 2,016 (issn: 1687-966X, eissn: 1687-9678)
  • Related identifiers: doi: 10.1155/2016/5178965, pmc: PMC4699043
  • Subject: Review Article | Internal medicine | RC31-1245 | Article Subject
    mesheuropmc: hemic and immune systems

All hematopoiesis cells develop from multipotent progenitor cells. Hematopoietic stem cells (HSC) have the ability to develop into all blood lineages but also maintain their stemness. Different molecular mechanisms have been identified that are crucial for regulating qu... View more
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