Translation elongation factor 1A facilitates the assembly of the tombusvirus replicase and stimulates minus-strand synthesis.

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Li, Zhenghe; Pogany, Judit; Tupman, Steven; Esposito, Anthony M.; Kinzy, Terri Goss; Nagy, Peter D.;

Replication of plus-strand RNA viruses depends on host factors that are recruited into viral replicase complexes. Previous studies showed that eukaryotic translation elongation factor (eEF1A) is one of the resident host proteins in the highly purified tombusvirus replic... View more