CRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesis.

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Ponferrada, Virgilio G.; Fan, Jieqing; Vallance, Jefferson E.; Hu, Shengyong; Mamedova, Aygun; Rankin, Scott A.; Kofron, Matthew; Zorn, Aaron M.; Hegde, Rashmi S.; Lang, Richard A.;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 7,issue 3 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC3299674, doi: 10.1371/journal.pone.0032635
  • Subject: Molecular Genetics | Signaling in Cellular Processes | Animal Models | Research Article | Biology | Molecular Cell Biology | Signal Transduction | Developmental Biology | Medicine | Organism Development | Anatomy and Physiology | Q | R | Molecular Development | Morphogenesis | Genetics | Signaling Pathways | Model Organisms | Cell Adhesion | Science

In multicellular organisms, morphogenesis is a highly coordinated process that requires dynamically regulated adhesion between cells. An excellent example of cellular morphogenesis is the formation of the neural tube from the flattened epithelium of the neural plate. Cy... View more
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