Quantitative Susceptibility Mapping Indicates a Disturbed Brain Iron Homeostasis in Neuromyelitis Optica - A Pilot Study.

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Doring, Thomas Martin; Granado, Vanessa; Rueda, Fernanda; Deistung, Andreas; Reichenbach, Juergen R.; Tukamoto, Gustavo; Gasparetto, Emerson Leandro; Schweser, Ferdinand;
(2016)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 11,issue 5 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC4865155, doi: 10.1371/journal.pone.0155027
  • Subject: Magnetic Resonance Imaging | Research Article | Diagnostic Medicine | Anatomy | Myelitis | Infectious Diseases | Diagnostic Radiology | Radiology and Imaging | Clinical Medicine | Neurodegenerative Diseases | Infectious Diseases of the Nervous System | Immunology | Globus Pallidus | Neurology | Thalamus | Autoimmune Diseases | Demyelinating Disorders | Biology and Life Sciences | Multiple Sclerosis | Research and Analysis Methods | Red Nucleus | Physiology | Medicine | Brain | Central Nervous System | Homeostasis | Q | R | Nervous System | Imaging Techniques | Clinical Immunology | Science | Medicine and Health Sciences | Physiological Processes

Dysregulation of brain iron homeostasis is a hallmark of many neurodegenerative diseases and can be associated with oxidative stress. The objective of this study was to investigate brain iron in patients with Neuromyelitis Optica (NMO) using quantitative susceptibility ... View more
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