Triglyceride-Increasing Alleles Associated with Protection against Type-2 Diabetes.

Article English OPEN
Yann C Klimentidis ; Akshay Chougule ; Amit Arora ; Alexis C Frazier-Wood ; Chiu-Hsieh Hsu (2015)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS Genetics, volume 11, issue 5 (issn: 1553-7390, eissn: 1553-7404)
  • Related identifiers: pmc: PMC4447354, doi: 10.1371/journal.pgen.1005204
  • Subject: QH426-470 | Research Article | Genetics
    mesheuropmc: nutritional and metabolic diseases | endocrine system diseases

Elevated plasma triglyceride (TG) levels are an established risk factor for type-2 diabetes (T2D). However, recent studies have hinted at the possibility that genetic risk for TG may paradoxically protect against T2D. In this study, we examined the association of geneti... View more