Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2

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Higgs, Martin R.; Sato, Koichi; Reynolds, John J.; Begum, Shabana; Bayley, Rachel; Goula, Amalia; Vernet, Audrey; Paquin, Karissa L.; Skalnik, David G.; Kobayashi, Wataru; Takata, Minoru; Howlett, Niall G.; Kurumizaka, Hitoshi; Kimura, Hiroshi; Stewart, Grant S.;
(2018)

Summary Components of the Fanconi anemia and homologous recombination pathways play a vital role in protecting newly replicated DNA from uncontrolled nucleolytic degradation, safeguarding genome stability. Here we report that histone methylation by the lysine methyltran... View more