Coexistence of TERT Promoter Mutations and the BRAF V600E Alteration and Its Impact on Histopathological Features of Papillary Thyroid Carcinoma in a Selected Series of Polish Patients

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Dagmara Rusinek; Aleksandra Pfeifer; Jolanta Krajewska; Malgorzata Oczko-Wojciechowska; Daria Handkiewicz-Junak; Agnieszka Pawlaczek; Jadwiga Zebracka-Gala; Malgorzata Kowalska; Renata Cyplinska; Ewa Zembala-Nozynska; Mykola Chekan; Ewa Chmielik; Aleksandra Kropinska; Roman Lamch; Beata Jurecka-Lubieniecka; Barbara Jarzab; Agnieszka Czarniecka;
(2018)
  • Publisher: MDPI
  • Journal: International Journal of Molecular Sciences,volume 19,issue 9 (issn: 1422-0067, eissn: 1422-0067)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.3390/ijms19092647, pmc: PMC6163174
  • Subject: Chemistry | papillary thyroid cancer | QD1-999 | TERTp mutation | <i>TERT</i>p mutation | BRAF V600E | <i>BRAF</i> V600E | Biology (General) | Article | QH301-705.5
    mesheuropmc: endocrine system diseases

TERT promoter (TERTp) mutations are important factors in papillary thyroid carcinomas (PTCs). They are associated with tumor aggressiveness, recurrence, and disease-specific mortality and their use in risk stratification of PTC patients has been proposed. In this study ... View more
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