A Candidate Gene Approach to ANCA-Associated Vasculitis Reveals Links to the C3 and CTLA-4 Genes but not to the IL1-Ra And Fc gamma-RIIa Genes

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Persson, Ulf; Gullstrand, Birgitta; Pettersson, Åsa; Sturfelt, Gunnar; Truedsson, Lennart; Segelmark, Mårten;
(2013)
  • Publisher: Karger: Open Access Journals / S. Karger AG
  • Journal: issn: 1420-4096, eissn: 1423-0143
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1159/000355744
  • Subject: Urology and Nephrology | Diseases of the genitourinary system. Urology | RC666-701 | ANCA; Genetics; Granulomatosis with polyangiitis; Microscopic polyangiitis; Wegeners granulomatosis | Microscopic polyangiitis | ANCA | Diseases of the circulatory (Cardiovascular) system | Microbiology in the medical area | Mikrobiologi inom det medicinska området | Urologi och njurmedicin | Medical and Health Sciences | Granulomatosis with polyangiitis | Wegener’s granulomatosis | RC870-923 | Genetics | Dermatology | Medicin och hälsovetenskap | RL1-803
    mesheuropmc: cardiovascular diseases

Background/Aims: The aim of the study is to search for associations between Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and polymorphisms in the genes of four key molecules possibly involved in different pathogenic pathways; complement C3, CTLA-... View more
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