Genetics of human and canine dilated cardiomyopathy

Article, Review English OPEN
Simpson, Siobhan; Edwards, Jennifer; Ferguson-Mignan, Thomas F.N.; Cobb, Malcolm; Mongan, Nigel P.; Rutland, Catrin S.;
  • Publisher: Hindawi Publishing Corporation
  • Journal: International Journal of Genomics,volume 2,015 (issn: 2314-436X, eissn: 2314-4378)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1155/2015/204823, pmc: PMC4525455
  • Subject: Review Article | QH426-470 | Genetics | cardiovascular disease, dilated cardiomyopathy | Article Subject
    mesheuropmc: complex mixtures | cardiovascular system | musculoskeletal system | cardiovascular diseases

Cardiovascular disease is a leading cause of death in both humans and dogs. Dilated cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third most common form of cardiac disease in humans and the second most common in dogs. In human studi... View more
  • References (141)
    141 references, page 1 of 15

    [1] J. M. Fleming, K. E. Creevy, and D. E. L. Promislow, “Mortality in north american dogs from 1984 to 2004: an investigation into age-, size-, and breed-related causes of death,” Journal of Veterinary Internal Medicine, vol. 25, no. 2, pp. 187-198, 2011.

    [2] C. D. Mathers and D. Loncar, “Projections of global mortality and burden of disease from 2002 to 2030,” PLoS Medicine, vol. 3, no. 11, article e442, 2006.

    [3] A. Egenvall, B. N. Bonnett, and J. Ha¨ggstro¨m, “Heart disease as a cause of death in insured Swedish dogs younger than 10 years of age,” Journal of Veterinary Internal Medicine, vol. 20, no. 4, pp. 894-903, 2006.

    [4] H. Raju, C. Alberg, G. S. Sagoo, H. Burton, and E. R. Behr, “Inherited cardiomyopathies,” British Medical Journal, vol. 343, Article ID d6966, 2011.

    [5] R. E. Hershberger, A. Morales, and J. D. Siegfried, “Clinical and genetic issues in dilated cardiomyopathy: a review for genetics professionals,” Genetics in Medicine, vol. 12, no. 11, pp. 655-667, 2010.

    [6] T.-B. Mausberg, G. Wess, J. Simak et al., “A locus on chromosome 5 is associated with dilated cardiomyopathy in doberman pinschers,” PLoS ONE, vol. 6, no. 5, Article ID e20042, 2011.

    [7] J. A. Dixon and F. G. Spinale, “Large animal models of heart failure: a critical link in the translation of basic science to clinical practice,” Circulation: Heart Failure, vol. 2, no. 3, pp. 262-271, 2009.

    [8] F. G. Akar, R. C. Wu, G. J. Juang et al., “Molecular mechanisms underlying K+ current downregulation in canine tachycardiainduced heart failure,” eTh American Journal of PhysiologyHeart and Circulatory Physiology, vol. 288, no. 6, pp. H2887- H2896, 2005.

    [9] M. Argenziano and M. L. Dickstein, “Cardiovascular eefcts of inhaled nitric oxide in a canine model of cardiomyopathy,” eTh Annals of oThracic Surgery , vol. 69, no. 5, pp. 1644-1645, 2000.

    [10] Y. Toyoda, M. Okada, and M. A. Kashem, “A canine model of dilated cardiomyopathy induced by repetitive intracoronary doxorubicin administration,” Journal of oThracic and Cardiovascular Surgery, vol. 115, no. 6, pp. 1367-1373, 1998.

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