JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex Traits.

Article, Other literature type English OPEN
Lips, E.S. ; Kooyman, M. ; de Leeuw, C.A. ; Posthuma, D. (2015)
  • Publisher: Multidisciplinary Digital Publishing Institute
  • Journal: Genes, volume 6, issue 2, pages 238-251 (issn: 2073-4425, eissn: 2073-4425)
  • Related identifiers: pmc: PMC4488663, doi: 10.3390/genes6020238
  • Subject: gene-set analysis | GWAS | QH426-470 | Genetics | genetic association | biological pathway | pathway analysis | Article

Gene-set analysis has been proposed as a powerful tool to deal with the highly polygenic architecture of complex traits, as well as with the small effect sizes typically found in GWAS studies for complex traits. We developed a tool, Joint Association of Genetic variants... View more
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