A Simple Three-Step Method for Design and Affinity Testing of New Antisense Peptides: An Example of Erythropoietin

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Nikola Štambuk; Zoran Manojlović; Petra Turčić; Roko Martinić; Paško Konjevoda; Tin Weitner; Piotr Wardega; Mario Gabričević;
  • Publisher: MDPI
  • Journal: International Journal of Molecular Sciences, volume 15, issue 6, pages 9,209-9,223 (issn: 1422-0067, eissn: 1422-0067)
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  • Identifiers: pmc: PMC4100090, doi: 10.3390/ijms15069209
  • Subject: Chemistry | peptide | modeling | QD1-999 | binding | Article | QH301-705.5 | thermophoresis | fluorescence | spectroscopy | Pharmacy | Biology (General) | erythropoietin | antisense

Antisense peptide technology is a valuable tool for deriving new biologically active molecules and performing peptide–receptor modulation. It is based on the fact that peptides specified by the complementary (antisense) nucleotide sequences often bind to each other with... View more
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